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The world of peptides therapy is a growing field in medicine ranging from improving skin care, growth hormone, to one’s immune system, to name a few.

Clinical Application of Peptide Therapies by Age Management Medicine,
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The world of peptides therapy is a growing field in medicine ranging from improving skin care, growth hormone, to one’s immune system, to name a few. On PubMed there are over 2.5 million articles on peptides. It is estimated that humans have over 250,000 peptides and we only understand a fraction of them. Peptides are chains of amino acids linked together by a polypeptide bond. The formation of a polypeptide bond by a dehydration synthesis will be reviewed. The difference of a peptide versus a protein will be delineated. In addition the mechanism of action on how peptides work will be reviewed.

CURRICULUM

INTRODUCTION TO PEPTIDES

Edwin N. Lee, M.D., FACE

BPC-157 FOR HEALING GASTRIC ULCERS AND SUPERIOR HEALING OF TENDINOPATHIES

Peptides—you have heard of them, but how and when do you use them? These simple short chains of amino acids regulate almost every known system and process in the body to include hormone production. In this lecture you will discover some of the uses of BPC-157. Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound that was discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including tendon to bone healing and healing of damaged ligaments. Additionally, BPC 157 seems to protect organs and to heal and prevent ulcers of the stomach. This peptide has also been demonstrated to reduce pain in areas of damaged tissue, mitigating the need for narcotic type medications. Individuals who are suffering from muscle sprains, tears, and damage can benefit from treatment with this unique peptide.

Rob Kominiarek, D.O., FACOFP

BRAIN HEALTH WITH CEREBROLYSIN AND OTHER PEPTIDES

Brain health is an important consideration for health and well-being. To date, drugs targeting a single pathological pathway have failed to show clinical efficacy for concussions, TBI, memory loss and dementia. Nootropic peptides are pleiotropic agents with effects on multiple mechanisms of brain injury that are an effective option to improve brain recovery and clinical outcome for restoring brain health.

Kathy O’Neil-Smith, M.D., FAARM

PEPTIDES TO INCREASE GROWTH HORMONE (CJC 1295, IPAMORELIN, TESAMORELIN, GHRP-6 AND OTHERS)

Growth hormone is an essential hormone in lowering body fat, improving on lipids, keeping muscles healthy and improving on bone density. Adult growth hormone deficiency symptoms will be reviewed and the association of higher mortality with growth hormone deficiency. Unfortunately the treatment with recombinant human growth hormone is not covered under most insurance plans and it is also cost prohibitive for most people. There is an alternative to the expensive recombinant human growth hormone mostly commonly used for boosting IGF-1 and has the advantage of inducing all five of the hGH isoforms rather just the one that is found in the synthetic form. CJC-1295, Ipamorelin, GHRP-6, Teslomorelin and others are peptides that have been shown to help improve IGF-1 levels.

Edwin N. Lee, M.D., FACE

PEPTIDES FOR SLEEP, IMPROVING TELOMERES, LIBIDO, REPRODUCTION AND MEMORY

It is estimated that there are about 250,000 peptides in the human body. We only understand a fraction of all the peptides. This talk will cover a wide range of issues. Delta Sleep Induced Peptide can help with restoring sleep. Epithalon is a peptide discovered by a famous Russia scientist Dr Khavinson. He has published extensively since the 1970’s and has published the longest human study on epithalon improving longevity and also increasing telomere lengths. A new drug is being developed to help with sexual dysfunction. This drug is the peptide Bremelanotide PT 141. The love peptide hormone kisspeptin will be reviewed. In addition Semax will be discussed to help with memory.

Edwin N. Lee, M.D., FACE

PEPTIDES FOR CANCER

Recent advances in peptide biology have found multiple peptides capable of exerting therapeutic benefits in the treatment of cancer. This lecture will discuss peptide classes, mechanisms of action and proposed protocols for incorporating peptide therapy in the treatment of cancer patients.

Luis Martínez, M.D., MPH

THYMOSIN PEPTIDES

Thymosins have been recognized as key peptides that help to regulate our immune system. As biological response modifiers, they are now being used in the treatment of disease with significant results and promise. These “new medicines”, based on discoveries in the areas of host immunity and regenerative medicine, have provided clinicians with additional treatment options in the treatment of autoimmune and infectious diseases. The thymosins can synergize with supplements and conventional therapies, increasing the effectiveness of the treatment protocol.

Kathy O’Neil-Smith, M.D., FAARM

PEPTIDES FOR AUTOIMMUNE DISEASE

Immune dysregulation, a universal characteristic of autoimmune diseases, can be targeted through the use of specific peptides. This lecture will present the rationale for utilizing peptide therapy in the management of autoimmune diseases. T-cell modulation, OGF axis and other mechanisms of action will be highlighted. Cases and protocols will be discussed.

Luis Martínez, M.D., MPH

PROTECTING YOURSELF IN AGE MANAGEMENT MEDICINE

Murderers, Rapists, and Terrorists have rights, but physicians do not! You are guilty and you can not prove your innocence. The facts are, a doctor can have a license sanctioned, suspended, revoked, limited, be bankrupted, disgraced, and made unemployable, based on an anonymous complaint that might have come from a disgruntled employee, a jealous competitor, an insurance company that doesn’t want to pay a bill, or a drug addict who wants a lighter sentence. And you have no right to know who the accuser is or even what you are being accused of committing. Board employees function as investigator, prosecutor, judge, jury, and executioner. The politically appointed members of the board almost always rubber-stamp what the board staff wants. The staff generally controls the flow of information to board members and accused doctors. The doctor has no right to cross-examine accusers, to ask that conflicted or biased staff be recused, or to challenge the evidence against him or her, which he might not even have seen. In short, modern day medical boards are the equivalent of medieval Consiglio dei Dieci only falling short by not being able to send you to the Judas Cradle. So how do you protect yourself? In this lecture we will explore the many avenues you can approach to provide as much protection as you can for your hard earned medical license.

Rob Kominiarek, D.O., FACOFP

3 PEPTIDES FOR A WELLNESS PRACTICE

There are about 300 theories of aging ranging from the neuroendocrine, free radical, cell membrane, Hayflick limit, mitochondria, cross link, autoimmune, glycation, and others. Most scientists have narrowed the specifics of what affects how we age down to 2 theories. The first group states that aging is natural and programmed into the body, while the second group of aging theories says that aging is a result of damage which is accumulated over time. Working on hormonal optimization, removing toxins, improving on nutrition, reducing stress, and increasing physical activity helps in slowing the aging process. In addition, using 3 peptides can also help in slowing the aging process. The peptides Epithalon, Thymosin Alpha 1 and BPC-157 help improve the telomeres, reduce inflammation, improve on the production of type 1 collagen and also improve the immune system. Pertinent medical studies on the 3 peptides will be reviewed in this talk.

Edwin N. Lee, M.D., FACE

PROGRESSIVE PEPTIDE THERAPY: A NEW THERAPEUTIC PARADIGM

Peptides are natural bio-regulators with diverse effects in the body and are emerging as a novel therapy for bio-regulation. Peptides function in cell-signaling and exert regulatory actions on neuro-endo-immune function. Presently, peptides are used in orthopedics, and neuro-endo-immune conditions for the treatment of injury, pain syndromes, IBD, brain health and immune system dysregulation.

Kathy O’Neil-Smith, M.D., FAARM

PANEL WITH Q & A

Edwin N. Lee, M.D., FACE
Kathy O’Neil-Smith, M.D., FAARM
Rob Kominiarek, D.O., FACOFP
Luis Martínez, M.D., MPH

FACULTY

ROB KOMINIAREK, D.O., FACOFP

Director, ReNue Health, Springboro, OH
Assistant Clinical Professor, Ohio University College of Osteopathic Medicine

Rob Kominiarek, D.O., FACOFP is a board-certified Fellow of the American College of Osteopathic Family Physicians and a Fellows Crest Award Winner in Family Medicine with advanced training in Age Management Medicine and Hormone Optimization. He is president and medical director of ReNue Health®. Dr. Rob is a graduate of the Nova-Southeastern University College of Osteopathic Medicine in Fort Lauderdale, FL. He completed his residency training at Ohio University, Grandview Hospital and Medical Center in Dayton, OH and is an Assistant Clinical Professor at Ohio University. An Amazon bestselling author and Executive Producer of a weekly health segment, ?Dr. Rob In the House? on NBC2 in Dayton, OH, Dr. Rob is a medical advisor and director to emergency medical services, police departments and radio and television shows across the country. He is a veteran of the United States Army with a passion directed towards overall health of the mind and body through proper nutritional habits, regular exercise, appropriate supplementation, and the intelligent optimization of hormones when clinically indicated. An avid athlete who enjoys cycling, swimming, triathlons, soccer, tennis, soaring, skiing Utah, Italian motorcycles, and automobile racing, Dr. Rob is a dedicated father who believes in practicing what he preaches, and as such lives a lifestyle dedicated towards healthy living and regular exercise.

EDWIN N. LEE, M.D., FACE

Assistant Professor of Internal Medicine, University of Central Florida College of Medicine, Orlando, FL
Founder, Institute for Hormonal Balance
Member, AMMG Conference Planning Committee

Dr. Edwin Lee is an endocrinologist, author and international speaker. Dr. Lee founded the Institute for Hormonal Balance, Orlando, FL in 2008, is board certified in Internal Medicine, Endocrinology, Diabetes and Metabolism, and has completed special training in Regenerative and Functional Medicine. Currently, he is the assistant professor of Internal Medicine at the University of Central Florida College of Medicine. In addition to writing his award winning books, “Your Amazing Heart,” “Your Awesome Brain,” “Feel Good Look Younger: Reversing Tiredness Through Hormonal Balance,” and “Your Best Investment: Secrets to a Healthy Body and Mind,” Dr. Lee has published many articles on internal medicine and endocrinology. He was also an author in the fourth edition of Textbook of Critical Care. His passion is healthy living and he practices what he preaches. He enjoys participating in open water swimming, cycling, hiking and Aquabike competition. Dr. Edwin Lee resides in Orlando, FL with his wife and 2 teenage boys.

LUIS MARTINEZ, M.D., MPH

President, Regenera Global, Ponce, Puerto Rico
President, XanoGene Clinic, San Juan, Puerto Rico

Dr. Luis Martínez is a Regenerative and Cell Therapy specialist, clinical researcher and biomedical consultant. He earned his medical degree at The Ponce School of Medicine and completed his residency training at the prestigious University of Pennsylvania. He also completed an Advanced Training Course in Stem Cells in Cancer at the Ponce Health Sciences University/Magee Research Institute consortium. He is board certified in Clinical Lipidology. Dr. Martinez holds a Masters of Public Health with a concentration in Epidemiology and is fellowship trained in Biosecurity. He is the president of XanoGene Clinic, which specializes in Regenerative and Age Management Medicine. He also founded and presides over Regenera Global, a multinational corporation specializing in biotech product development, research, and clinical consulting. Dr. Martinez has advised and helped set up various clinics and laboratories in Latin America within the Regenerative Medicine space. He also serves on the advisory board for various biotech companies and professional societies. He is actively involved in educating and training physicians in multiple aspects of Regenerative and Age Management Medicine.

KATHY O’NEIL-SMITH, M.D., FAARM

Private Internal, Integrative and Regenerative Medicine Practice, Newton, MA

Dr. Kathleen O’Neil-Smith is a magna cum laude graduate of Boston University Medical School. She completed an internship in pathology at Massachusetts General Hospital followed by an internship and residency in internal medicine at the Brigham and Women’s Hospital in Boston. In 2008, she completed a two-year fellowship in functional medicine through the American Academy of Anti-Aging and Regenerative Medicine, as well as a Stem Cell Fellowship at A4M and a TBI certification at AMMG. She has been on the faculty at Tufts University School of Medicine and Boston University School of Medicine. She competed as a member and later coach, of the United States Women’s National Rowing Team and continues to race competitively every year at The Head of The Charles Regatta in Boston. Dr. O’Neil-Smith is Medical Director at TB12 Sports Center in Foxboro, MA. She is a compassionate, innovative and conscientious physician, committed to excellence, and dedicated to offer the most cutting edge safe therapies to her patients.

CME

ACCREDITATION / LEARNER NOTIFICATION

Satisfactory Completion

Learners must complete an evaluation form to receive a certificate of completion. Your chosen sessions must be attended in their entirety. Partial credit of individual sessions is not available. If you are seeking continuing education credit for a specialty not listed below, it is your responsibility to contact your licensing/certification board to determine course eligibility for your licensing/certification requirement.

Physicians

In support of improving patient care, this activity has been planned and implemented by Amedco LLC and Age Management Medicine Group. Amedco LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation Statement – Amedco LLC designates this live activity for a maximum of 8.25 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Objectives – After attending this program you should be able to:

Understand the overall use of Peptides in medicine, how they serve as bio regulators and discuss the science, published studies and chemical make-up of Peptides.
Learn and understand how to clinically use Peptides within the limits of the Law and within the guidelines of State Medical Boards.
Understand evidence based science behind the clinical use of Peptides for Delta Induced Sleep, Memory Restoration, Brain Health, Cancer, Immune System Dysregulation and Function, Auto Immune Disease, Increase IGF-1 Levels, Increased Telomere Length, Wound Healing and Sexual Enhancement.

LEARNING OBJECTIVES

Complete Peptides Course Objectives:

Understand the overall use of Peptides in medicine, how they serve as bio regulators and discuss the science, published studies and chemical make-up of Peptides.
Learn and understand how to clinically use Peptides within the limits of the Law and within the guidelines of State Medical Boards.
Understand evidence based science behind the clinical use of Peptides for Delta Induced Sleep, Memory Restoration, Brain Health, Cancer, Immune System Dysregulation and Function, Auto Immune Disease, Increase IGF-1 Levels, Increased Telomere Length, Wound Healing and Sexual Enhancement.

INSTRUCTIONS FOR OBTAINING CME CREDIT

Complete ALL lessons in this series.
Read the Learner Notification.
Complete the Course Evaluation at the end of each lesson.
At the completion of the Course Evaluation you will be taken to a screen where you can immediately print a copy of your CME Certification. IMPORTANT NOTE: Do not exit until you have completed both the Course Evaluation and the CME Certificate
A copy will also be emailed to the address you used to sign up.

Unrestricted Educational Grant provided by Tailor Made Compounding Pharmacy.

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Status	Available
Total size	1.5 GB
Format	mp4, pdf, png
Language	English
Author	Age Management Medicine